The clear path to small molecule visualization & quantification

Custom mouse monoclonal antibodies against small molecules

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Advantages of small molecule monoclonal antibodies

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  • High specificity & affinity – Internal selection protocols are implemented to ensure our mAbs translate into robust and accurate immunoassays.
  • Cross-species reactivity – Unlike proteins, small molecules are conserved throughout phylogenesis. A single small molecule mAb can thus be applied to virtually any biological sample.
  • High reproducibility & availability – Produced in vitro by a single immortalized cell clone, our monoclonal antibodies meet industrial standards for quality and scalability.

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Our approach for the development of small molecule mAbs

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  • A personalized strategy for antigen design, based on an in-depth analysis of the physico-chemical properties, immunogenicity and potential competitors of the small molecule target to address, tailored to your intended use of the antibody.
  • Quality controls, deliverables, Go/No-Go decision points at the end of each phase, to ensure transparent projects with limited risk and deferred costs.
  • Full ownership of the antibody-producing clone is granted to the client at the end of the study, together with at least 2mg of purified monoclonal immunoglobulin.

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Additional options & services

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  • Custom molecule synthesis
  • Antigen coupling validation by NMR

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  • Measurement of antibody binding affinity by surface plasmon resonance (Biacore)
  • Complementary antibody production and purification

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  • Antibody validation for IHC, IF, ICC, ELISA, …
  • …

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